| LG regular-season | Vancouver Whitecaps def. Seattle Sounders FC 0-2 |
| LG regular-season | FC Dallas def. Austin FC 1-2 |
| LG regular-season | Chicago Fire FC def. Portland Timbers 2-1 |
| LG regular-season | Philadelphia Union def. New York City FC 2-3 |
| LG regular-season | St. Louis CITY SC def. San Jose Earthquakes 1-3 |
| LG regular-season | San Diego FC def. LAFC 0-1 |
| LG regular-season | Colorado Rapids def. Sporting Kansas City 2-0 |
| LG regular-season | Houston Dynamo FC def. LA Galaxy 1-0 |
| LG regular-season | Nashville SC def. Inter Miami CF 4-1 |
| LG regular-season | Atlanta United FC def. Red Bull New York 2-1 |
| LG regular-season | Toronto FC def. New England Revolution 2-1 |
| LG regular-season | Charlotte FC def. Columbus Crew 3-1 |
| LG regular-season | Houston Dynamo FC def. New England Revolution 0-2 |
| LG regular-season | Portland Timbers def. Seattle Sounders FC 2-1 |
| LG regular-season | FC Cincinnati def. San Jose Earthquakes 4-2 |
| LG regular-season | Houston Dynamo FC def. Sporting Kansas City 0-2 |
| LG regular-season | Red Bull New York def. Orlando City SC 3-2 |
| LG regular-season | Philadelphia Union def. Atlanta United FC 3-2 |
| LG regular-season | MLS All-Stars def. Liga MX All-Stars 4-3 |
| LG regular-season | San Diego FC def. FC Dallas 1-0 |
| LG regular-season | Columbus Crew def. FC Cincinnati 2-1 |